Mixed Glycoprotein B Genotypes of Cytomegalovirus and Immunosuppression
نویسندگان
چکیده
منابع مشابه
Mixed glycoprotein B genotypes of cytomegalovirus and immunosuppression.
Cytomegalovirus (CMV) infection remains the most significant infection affecting the outcome of solid-organ trans-plantation or hematopoietic stem cell transplantation (HSCT). CMV infection causes febrile illness and end-organ disease and has been implicated indirectly in other clinically relevant outcomes. CMV infection has been shown to reduce patient survival and graft success rates and to i...
متن کاملMixed cytomegalovirus glycoprotein B genotypes in immunocompromised patients.
On the basis of sequence variation in the UL55 gene that encodes glycoprotein B (gB), human cytomegalovirus (CMV) can be classified into 4 gB genotypes. The goal of the present study was to determine the distribution of CMV gB genotypes and the effect of gB type on clinical outcomes in a cohort of immunocompromised patients, including both transplant recipients and nonrecipients. The distributi...
متن کاملCytomegalovirus glycoprotein B genotypes in Mexican children and women.
OBJECTIVE Cytomegalovirus (CMV) is widely distributed and constitutes the main cause of congenital infections worldwide. CMV transmission during pregnancy represents one of the major impacts of this virus on public health. This study aimed at assessing glycoprotein B (gB) CMV genotypes in Mexican children and pregnant women, since there is limited information regarding CMV genomic diversity in ...
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conclusions in this study, high prevalence of 91.7% hcmv gb1 genotype was predominant among hcmv-positive uc patients, which suggests that there might be an association between hcmv gb genotype 1 and uc disease. results among 98 patients with uc, only 12 (12.2%) patients were positive for hcmv genome, while the hcmv genome was not detected in any of the controls. (p = 0.002). the distribution o...
متن کاملOccurrence of Human Cytomegalovirus Glycoprotein B Genotypes in Immunocompetent and Immunosuppressed Taiwanese Patients
Objectives: To investigate the differences of genotypic distributions among isolates between immunosuppressed and immunocompetent patients in a Taiwanese population. Methods: Human cytomegalovirus (HCMV) isolates from 76 patients with adequate chart data were analyzed. Polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) was used to define gB genotypes which include gB1...
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ژورنال
عنوان ژورنال: Clinical Infectious Diseases
سال: 2004
ISSN: 1058-4838,1537-6591
DOI: 10.1086/421500